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March 2, 1970

Acute Renal Failure and Transient Hypercalcemia in Idiopathic Rhabdomyolysis

Author Affiliations

From the Department of Medicine, University of Washington, Seattle.

JAMA. 1970;211(9):1539-1540. doi:10.1001/jama.1970.03170090055014

Acute renal failure in association with idiopathic rhabdomyolysis developed in a 29-year-old man. Symptomatic hypercalcemia occurred during the diuretic period and was accompanied by hypercalciuria, elevated serum alkaline phosphatase level, decreased tubular reabsorption of phosphate, and an increased serum parathyroid hormone level. Transient hyperparathyroidism is suggested as the primary mechanism responsible for this unusual complication of acute renal failure and physicians are alerted to this potential hazard.