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February 4, 1974

Ectopic Calcification In Sarcoidosis

Author Affiliations

Los Angeles

JAMA. 1974;227(5):556. doi:10.1001/jama.1974.03230180054019

To the Editor.—  Hypercalcemia in some patients with sarcoidosis may lead to calcification in the kidneys and other tissues, including the soft tissues of the shoulder, the pulp of the fingers, the metatarsophalangeal joint of the big toe, and the ear cartilage.1-4 We report an example.

Report of a Case.—  A 65-year-old woman complained in 1962 of blurry vision and shortness of breath on exertion. The chest roentgenogram showed bilateral diffuse reticulonodular infiltration. Noncaseating sarcoid granulomas were found on a scalene-node biopsy negative for acid-fast bacteria. The patient was treated with corticosteroids.During the course of her illness, the patient was plagued by recurrent uveitis, chorioretinitis, and glaucoma. In 1963, an x-ray film taken when the patient complained of pain in the abdomen revealed a calculus in the lower pole of the right kidney. In 1964, cor pulmonale was controlled with digitalis and diuretics.During the course of the