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March 30, 1970

Frozen Section Diagnosis Of Endometrial Carcinoma

Author Affiliations

Castro Valley, Calif

JAMA. 1970;211(13):2156. doi:10.1001/jama.1970.03170130052015

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To the Editor.—  In replying to an inquiry concerning endometrial adenocarcinoma, Dr. Alfred I. Sherman declares, "The diagnosis of endometrial carcinoma by frozen section is... unreliable" (210:2291, 1969). We do not agree with this statement.Today, nearly all pathologists utilize modern reliable freezing microtome techniques for preparation of frozen sections for rapid diagnosis. Even before the advent of the cryotome, diagnosis of endometrial lesions was being made by many pathologists from frozen sections of curettings, and with great reliability.The cryotome has brought the technique within the reach of any pathologist who has such an instrument and the ability to use it. This instrument is as essential to current practice of surgical pathology as the compound microscope.Diagnosis of any lesion by frozen section examination is rarely "unreliable"; a competent surgical pathologist either recognizes the lesion and reports the diagnosis accordingly, or his examination of the frozen section (or