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March 4, 1974

Hepatitis B Antigen and Antibody: Occurrence in Families of Asymptomatic HB Ag Carriers

Author Affiliations

From the Department of Virus Diseases, Division of Communicable Diseases and Immunology (Drs. Irwin, Bancroft, and Russell and Messrs. Karwacki and Pinkerton) and Division of Preventive Medicine (Dr. Allen), Walter Reed Army Institute of Research, Washington, DC. Dr. Allen is now with the Letterman Army Institute of Research, San Francisco.

JAMA. 1974;227(9):1042-1043. doi:10.1001/jama.1974.03230220032011

A serologic survey for HB Ag and antibody in 17 families, each with one adult who was an asymptomatic HB Ag carrier, demonstrated an increased frequency of hepatitis B infection in family contacts of the carrier.