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March 25, 1974

Myoglobinuria Precipitated by Viral Infection

Author Affiliations

From the Clinical Virology Laboratory (Dr. Berlin), Passavant Pavilion, Northwestern Memorial Hospital, and the departments of neurology and pathology (Drs. Bovner and Berlin), and the Nephrology Section (Dr. Simon), and Infectious Diseases/Hypersensitivity Section (Dr. Berlin) of the Department of Medicine, Northwestern University Medical School.

JAMA. 1974;227(12):1414-1415. doi:10.1001/jama.1974.03230250038029

A 30-year-old man had an episode of acute myoglobinuria in association with infection due to type A2 (Hong Kong) influenza virus in December 1968. He was well until he again experienced myoglobinuria in July 1972. This episode was in association with a coxsackievirus B5 infection. The occurrence of two separate instances of myoglobinuria with demonstrated virus infections is interpreted as clear evidence that virus infections can precipitate rhabdomyolysis.