Nonocclusive ischemia of the lower extremities may be mistakenly diagnosed as thrombotic or embolic arterial occlusion. This is particularly true when there is asymmetrical involvement of the extremities. Doppler ultrasound flowmeter recordings may be helpful in suggesting the diagnosis, but arteriography is essential for the differentiation between occlusive and nonocclusive states. By confirming arterial patency, needless and often hazardous surgery can be avoided.
Dardik H, Dardik I, Spreyregen S, Veith FJ. Asymmetrical Nonocclusive Ischemia of the Lower Extremities. JAMA. 1974;227(12):1417–1419. doi:10.1001/jama.1974.03230250041031
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