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April 13, 1970

Hollander Test Unnecessary

Author Affiliations

University of Florida Gainesville

JAMA. 1970;212(2):320. doi:10.1001/jama.1970.03170150074021

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To the Editor.—  I have just read with much interest and some concern the article entitled "Hollander Test May Cause Dangerous Arrhythmia" which appeared in Medical News (210:2005,1969). Since I introduced the operation of vagotomy in the treatment of peptic ulcer, I am naturally concerned with all aspects of this operation. I believe that the Hollander test should be abandoned except perhaps in a few patients where it is desirable to determine if a previous vagotomy has been complete or not. In almost all cases a measurement of the basal or fasting gastric secretion is a more useful and accurate procedure. In the patient with a duodenal ulcer, the secretion of acid by the fasting empty stomach is usually three to five times normal. If the basal secretion has not been reduced by vagotomy, the cause is usually the presence of an undiagnosed Ellison-Zollinger tumor or to failure to