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June 13, 1977

Cerebral Arterial Disease

JAMA. 1977;237(24):2651. doi:10.1001/jama.1977.03270510073034

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Great advances have been made in the understanding of the epidemiology and physiological and anatomical pathology of cerebrovascular disease and in diagnostic methods useful in the investigation of strokes. "It must be admitted that these advances, although valuable as indicators of how cerebral vascular disease may be prevented, have not been matched by similar spectacular changes in the field of therapy of established strokes." Thus, Dr R. W. Ross Russell, the editor of this book, sums up the contents in his preface. Nor, one may add, is the True Way so clear-cut in the prevention of stroke in patients with transient ischemic attacks. After years of heady enthusiasm for the use of various methods of anticoagulation or of vasodilation, it is sobering to reflect that the humble aspirin in many instances defines the limits of therapeutic undertaking. The efficacy of this type of treatment is yet to be established: perhaps