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April 15, 1974

Early Histological Diagnosis of Cervical Cancer

Author Affiliations

Massachusetts General Hospital Boston

JAMA. 1974;228(3):400. doi:10.1001/jama.1974.03230280100047

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This attractive volume presents a minutely detailed account of the early development of cervical cancer based on an extensive review of the literature and the author's own painstaking studies. The final reconstruction of events is stimulating because of the presentation of new data and several unorthodox interpretations. As one example, the evidence for a progression of dysplasia through carcinoma in situ into invasive carcinoma is challenged. The author emphasizes that dysplasia and carcinoma in situ have separate sites of origin in the cervix, and invasive carcinoma may be associated with the former as well as the latter.

The major faults of the text are its organization and style. The sequence of presentation is such that full comprehension of the earlier chapters and pictures depends on reading and viewing those that appear later. The inevitable repetition that results, the occasional verbosity and lack of clarity of the text contribute to difficult