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April 29, 1974

The Structure and Function of Muscle, vol 2, Part 2: Structure

Author Affiliations

University Hospitals Iowa City

JAMA. 1974;228(5):633. doi:10.1001/jama.1974.03230300059038

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This second volume in this series completes the outstanding and comprehensive portrayal of muscle structure begun in volume 1. In this, as in the companion issues, eminently qualified investigators summarize current knowledge of their assigned topic with remarkable clarity. This work continues the discussion of specialized types of muscle—eg, uterus and heart. It describes not only the microanatomy of muscle but also the skeletal muscle regeneration process.

The uterus serves as a model for a description of smooth muscle contractile elements, mechanism of contraction, and the effect of numerous hormones. The author then lists the clinical implications of several of these.

The dynamic implications of cardiac muscle necessitate an understanding of cell boundaries and electrical properties so well elucidated in this book.

A section on microanatomy including that of smooth, skeletal and cardiac muscle, explains skeletal muscle structure, including ultrastructure, and discusses hypertrophy, red and white muscle, musculotendinous junctions, and