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July 11, 1977

Systemic Absorption of Neomycin Irrigating Solution

Author Affiliations

From the Departments of Infectious Disease (Drs Weinstein and McHenry) and Microbiology (Dr Gavan), Cleveland Clinic Foundation, Cleveland.

JAMA. 1977;238(2):152-153. doi:10.1001/jama.1977.03280020056025

Systemic absorption of neomycin sulfate occurred in ten patients in whom neomycin wound irrigating solutions were used during total hip replacement. The use of neomycin in this manner may be associated with the risk of ototoxicity and nephrotoxicity.

(JAMA 238:152-153, 1977)