Systemic absorption of neomycin sulfate occurred in ten patients in whom neomycin wound irrigating solutions were used during total hip replacement. The use of neomycin in this manner may be associated with the risk of ototoxicity and nephrotoxicity.
(JAMA 238:152-153, 1977)
Weinstein AJ, McHenry MC, Gavan TL. Systemic Absorption of Neomycin Irrigating Solution. JAMA. 1977;238(2):152–153. doi:10.1001/jama.1977.03280020056025
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