[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
May 6, 1974

Mycoplasma pneumoniae Pneumonia and Clindamycin Therapy: Failure to Demonstrate Efficacy

Author Affiliations

From the US Walson Army Hospital, Fort Dix, New Jersey (Dr. Smilack); Brooke General Hospital, Fort Sam Houston, Texas (Drs. Bergin and Moore); and the University of Texas Southwestern Medical School, Dallas (Dr. Sanford).

JAMA. 1974;228(6):729-731. doi:10.1001/jama.1974.03230310039025

A double-blind study was undertaken to evaluate the efficacy of clindamycin hydrochloride hydrate as compared with tetracycline hydrochloride and placebo in the treatment of Mycoplasma pneumoniae. Thirty-two young adult men were studied. Clindamycin failed to cause defervescence or roentgenographic resolution more promptly than placebo. Tetracycline was associated with a shortening of the duration of fever.

(JAMA 228:729-731, 1974)