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May 6, 1974

ICU-Acquired Pneumonia Due to Flavobacterium meningosepticum

Author Affiliations

From the Department of Anaesthesia, Harvard Medical School and Beth Israel Hospital, Boston.

JAMA. 1974;228(6):732. doi:10.1001/jama.1974.03230310042026

FLAVOBACTERIUM meningosepticum is a nonfermentative Gramnegative bacillus that is extremely resistant to the potent aminoglycosides and polymyxins, yet sensitive to antibiotics that act primarily on Gram-positive bacteria. Known to cause meningitis in premature and newborn infants,1F. meningosepticum has also been identified in contaminated anesthetic vials in an epidemic in an operating room.2

Report of a Case  A 14-year-old girl fell from a horse and, despite the protection of a helmet, became comatose.The patient's history was unremarkable except for hayfever. Her temperature was 38.3 C (101 F); blood pressure was 120/70 mm Hg. There was bilateral decerebrate posturing. The left pupil measured 3.5 mm; the right, 2.5 mm. The left ocular disk was blurred, without pulsations; the right ocular disk was not blurred. There were no extraocular eye movements, and ice-water caloric stimulation did not produce nystagmus. There was brisk bilateral extensor toe response.Lumbar puncture showed