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July 18, 1977

Age-Specific Incidence Rates Of Endometrial Cancer

JAMA. 1977;238(3):213. doi:10.1001/jama.1977.03280030021012

To the Editor.—  I am writing to support the conclusions of Proudfit and Austin in LETTERS (237:958-959, 1977) that the incidence of uterine corpus cancer, an age-specific disease, should be reported in age-specific rates. An earlier analysis of data generated by the Connecticut Tumor Registry (CTR) showed no change in the age-adjusted rates of endometrial cancer between 1935 and 1969.1 Because we felt that age-adjusted rates may not realistically reflect an actual change in the incidence of a disease that experience has shown to be most commonly diagnosed in specific older age groups, we used the Yates modification of chi-square analysis to examine the incidence rates of corpus cancer reported to the CTR between 1953 and 1973. We found a most significant (P <.001) increase in the diagnosis of this disease in the age groups most affected as well as an impressive trend toward increasing diagnosis of this