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July 18, 1977

Sign of Leser-Trélat

JAMA. 1977;238(3):236-237. doi:10.1001/jama.1977.03280030044020

We report a case of squamous cell carcinoma of the lung associated with the sudden appearance of seborrheic keratosis and acquired ichthyosis. We conclude that the sign of Leser-Trélat is a rare cutaneous manifestation of internal malignant disease.

(JAMA 238:236-237, 1977)