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July 25, 1977

Progress in Cardiology—5

JAMA. 1977;238(4):350. doi:10.1001/jama.1977.03280040070036

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Progress in Cardiology—  5 is written specifically for the cardiologist, the cardiovascular physiologist, and the internist with a pronounced interest in cardiology and cardiovascular research. The book begins with a sixchapter symposium on coronary blood flow. Kloeke describes physiological mechanisms that regulate coronary blood flow in the normal and abnormal myocardium. Heart rate, preload, afterload, and contractility are listed by Parmley as the primary determinants of myocardial oxygen demand. These factors are more readily manipulated by the clinician than attempts to improve myocardial oxygen supply. Specific supply-demand ratios in pathological states are discussed by Hoffman and Buckberg. Kloeke summarizes methods for measuring coronary flow, regional flow, and graft flow to the myocardium. This long chapter overlaps with the ensuing chapter in which Masesi presents measurements of myocardial blood flow. External counting, steady imaging, and dynamic regional recording for evaluating coronary blood flow is discussed in the final chapter on coronary blood