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August 1, 1977

Human Reovirus-like Agent InfectionOccurrence in Adult Contacts of Pediatric Patients With Gastroenteritis

JAMA. 1977;238(5):404-407. doi:10.1001/jama.1977.03280050044018

Sixty-four adult family contacts of 61 young patients with gastroenteritis were included in a study for evidence of concurrent infection with the human reovirus-like agent (HRVLA) of infantile diarrhea. Evidence of infection was detected in 26 (41%) of the adult contacts. The HRVLA infection occurred significantly more often among adult contacts of pediatric patients infected with HRVLA (55%) than among contacts of young patients not infected with the agent (17%). Mild cases of gastroenteritis developed in only three of the contacts infected with HRVLA.

(JAMA 238:404-407, 1977)