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May 27, 1974

Spurious Thrombocytopenia

Author Affiliations

Montefiore Hospital Bronx, NY

JAMA. 1974;228(9):1098. doi:10.1001/jama.1974.03230340014010

To the Editor.—  "Spurious Thrombocytopenia" (227:628, 1974) reminds me of an example.A platelet count of 30,000/cu mm appeared in a 60-year-old man who had never had a hematologic problem or malignant disease. Tonsillectomy and prostatectomy had previously been performed without a bleeding problem. A second platelet count was 20,000/cu mm, and this was done by Technicon platelet counter with the blood collected in edetic acid as usual. Peripheral smear by finger stick at bedside showed an adequate number of platelets. There were no platelet clumps, giant platelets, or platelet satellitism. Blood collected in citrated and heparinized tubes showed normal numbers of platelets by the same machine counter. The changes of temperature of the blood specimen tubes (4 C, 20 C) did not alter the platelet counts. The blood smears made with edetic acid-treated blood had many platelet clumps, more than half larger than white blood cells. Also, no giant