[Skip to Content]
[Skip to Content Landing]
May 27, 1974

Renal Transplantation Between Adults and ChildrenDifferences in Renal Growth

JAMA. 1974;228(9):1143-1145. doi:10.1001/jama.1974.03230340045031

There is an impressive but purely compensatory growth response of the child's kidney transplanted into the uremic adult, but no hypertrophy or hypotrophy of the adult's kidney in the uremic child.

Two separate types of renal growth seem to occur. Compensatory hypertrophic growth is a rapid reversible response to a functional nephron deficit. Obligatory growth occurs as one grows up, and is not reversible.

(JAMA 228:1143-1145, 1974)