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August 15, 1977

Medical News

JAMA. 1977;238(7):571-578. doi:10.1001/jama.1977.03280070011001

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No such thing as `localized' arteriosclerosis, say surgeons  Patients with arteriosclerosis in one area of the body increasingly are undergoing closer scrutiny of blood flow in all major vessels, particularly those supplying the heart.The grave implications of localized peripheral arteriosclerosis were underscored recently in a ten-year follow-up report on 103 patients who had been given autogenous venous femoropopliteal bypass grafts. The patients had had either intermittent claudication, pain at rest, or gangrene of the legs as a result of the arteriosclerotic process.Thirty-six of the patients eventually died of myocardial infarction, said James A. DeWeese, MD, chairman of the Department of Surgery at the University of Rochester School of Medicine. Twenty-one of these had had no previous history of coronary artery disease. Another 11 patients died of complications of arteriosclerosis: cerebrovascular thrombosis (five), mesenteric artery occlusion (two), and nephrosclerosis (four).Dr DeWeese spoke to the Society for Vascular