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June 10, 1974

Ultrastructure of Haemic Cells: A Cytological Atlas of Normal and Leukaemic Blood and Bone Marrow

Author Affiliations

Cook County Hospital Chicago

JAMA. 1974;228(11):1433. doi:10.1001/jama.1974.03230360057034

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The field of hematology now has a compact, high-quality ultrastructure atlas of normal and malignant bone marrow elements. The 157 photomicrographs are of superior technical quality and include two common stains, acid phosphatase and peroxidase, for the elaboration on the standard electron microscopic morphology.

Each of the major sections and subsections begins with a masterly, brief, but complete description of ultrastructure and its progressive development in the cellular line under consideration. Since this is a text for advanced students of hematology, no light microscopic photographs are included for orientation.

The number of photomicrographs for a given stage of the cell line are generous enough to demonstrate the numerous normal variations typical of sequential development. Legends for each figure are lucid, exact, and complete. Both the textual material and the legends clearly identify areas of controversy or uncertainty as to origin, function, or artifact. The text and legends are well referenced