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July 8, 1974

Medical News

JAMA. 1974;229(2):121-130. doi:10.1001/jama.1974.03230400001001

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More use of serological tests would reduce candidiasis problem  Immunodiffusion or counterelectrophoresis tests, when used in combination with latex agglutination tests, can detect invasive candidiasis in compromised patients. The tests are not new, but have not been used to their capacity in these patients, says Layne Gentry, MD, assistant professor of medicine at Baylor College of Medicine.Standardization of the tests is being carried out by Leo Kaufman, PhD, chief of the Fungus Immunology Branch at the Center for Disease Control, in Atlanta. When this work is completed, the tests will probably be recommended as part of the routine analysis of cancer patients, and of all patients taking immunosuppressive drugs concurrent with broad spectrum antibiotics, Dr. Gentry told Medical News.Candidiasis is the most common fungus infection seen in cancer patients, Dr. Gentry said, but it is hard to distinguish the frequent colonization of the organism from true early