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Article
September 19, 1977

Nonhemorrhagic Decrements in Hematocrit Values After Percutaneous Renal Biopsy

Author Affiliations

From the Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Va.

JAMA. 1977;238(12):1266-1268. doi:10.1001/jama.1977.03280130048014
Abstract

Seventy patients without bleeding after a percutaneous renal biopsy (PCB) were studied to define the incidence of decrements in hematocrit values, hypotension, and bradycardia. Hematocrit values decreased 0.5% in 60% of the patients, ≥1% in 44%, and ≥2% in 34% of patients. After PCB, an increase of ≥1% occurred in 55% of the patients with hematocrit nadirs of ≥1%. Hematocrit values increased 3.0%±0.6% in 8/19 patients with a previous decrease of ≥2% but continued to decrease in 13% of the patients. A weight gain or positive fluid balance occurred in 29%, hypotension in 7%, and relative bradycardia in 4% of the patients. These studies show that a decrease in hematocrit values and hypotension may occur in patients after PCB without bleeding. This may result from hemodilution and increased parasympathetic discharge and as part of a natural spectrum of decreasing hematocrit levels coincident with PCB.

(JAMA 238:1266-1268, 1977)

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