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July 8, 1974

The Biochemical Basis of Neuropharmacology

Author Affiliations

International Drug Therapy Newsletter Baltimore

JAMA. 1974;229(2):211. doi:10.1001/jama.1974.03230400071048

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This well-printed, easy-to-read book is based on a course given by the authors for undergraduate seniors, and graduate and medical students at Yale. Now that I have read it, I envy those privileged to take the course. If the authors lectured as clearly as they write, then they imparted a tremendous amount of information on certain aspects of the cellular foundations of neuropharmacology and the biochemistry of the central nervous system, with special emphasis on the neurotransmitters.

In this second edition, the chapters have been up-dated with new information, so much so that there are now two chapters on the catecholamines because of coverage of recent findings on dopamine. New material on the prostaglandins, cyclic adenosine monophosphate (AMP), and the cholinergic receptor also has been added. Finally, more attention is given to drugs and to neurological diseases. At the end of each chapter, there is an excellent listing of carefully