Cimetidine, a potent H2-receptor antagonist, has been introduced for the treatment of various conditions associated with acid peptic digestion in the gastrointestinal tract. Preliminary results are encouraging. Adverse reactions do not appear to be substantial; however, the effect of long-term use has yet to be ascertained.
(JAMA 238:1289-1290, 1977)
Clayman CB. Evaluation of Cimetidine (Tagamet): An Antagonist of Hydrochloric Acid Secretion. JAMA. 1977;238(12):1289–1290. doi:10.1001/jama.1977.03280130071025
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