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September 19, 1977

Evaluation of Cimetidine (Tagamet)An Antagonist of Hydrochloric Acid Secretion

JAMA. 1977;238(12):1289-1290. doi:10.1001/jama.1977.03280130071025

Cimetidine, a potent H2-receptor antagonist, has been introduced for the treatment of various conditions associated with acid peptic digestion in the gastrointestinal tract. Preliminary results are encouraging. Adverse reactions do not appear to be substantial; however, the effect of long-term use has yet to be ascertained.

(JAMA 238:1289-1290, 1977)