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Article
July 29, 1974

Dipyridamole for Proteinuria SuppressionUse in a Patient With Proliferative Glomerulonephritis

JAMA. 1974;229(5):557-558. doi:10.1001/jama.1974.03230430049028
Abstract

DIPYRIDAMOLE is said to reduce platelet adhesiveness and thrombus formation1 and to be effective in preventing glomerular lesions when used in combination with anticoagulants.2 We tested it alone in a patient with proliferative glomerulonephritis and found that it corrected proteinuria.

Report of a Case  A 17-year-old boy was admitted to the hospital because of proteinuria and hematuria on Feb 29, 1972. He had been well until about three months before, when he had proteinuria (1 + ) at the time of periodical examination. A month before admission he caught a cold. Several weeks later he noticed hematuria and visited the hospital. He denied having had recurrent tonsillitis. The temperature was 36.0 C (96.8 F) and the pulse rate was 72 beats per minute. The blood pressure was 120/70 mm Hg. Results of physical examination were normal.The urine gave 3+ test for protein; the sediment contained abundant red blood cells (RBCs)

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