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October 10, 1977

Complete Disappearance of Osteoblastic Metastasis in Prostatic Carcinoma

JAMA. 1977;238(15):1630. doi:10.1001/jama.1977.03280160024011

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To the Editor.—  The disappearance of osteoblastic metastasis originating from carcinoma of the prostate as described by Catane et al (237:2471, 1977) is not unique to estramustine phosphate. We have a case of complete radiographic disappearance of an osteoblastic metastasis from a carcinoma of the prostate following orchiectomy alone,

Report of a Case.—  A 52-year-old man was seen with acute urinary retention in 1969. He underwent a transurethral resection of the prostate and was found to have an anaplastic adenocarcinoma of the prostate. On that admission he was found to have an asymptomatic osteoblastic metastasis of his L-2 vertebral body; this was confirmed by needle biopsy of that vertebra (Fig 1). He underwent bilateral orchiectomy and was discharged without estrogenic therapy. This patient was again seen in 1973 in urinary retention and underwent a repeat transurethral resection. At that time it was noted that he had a complete roentgenographic clearing