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Article
August 12, 1974

"Bull's-Eye" LesionsSolitary or Multiple Nodules in the Gastrointestinal Tract With Large Central Ulceration

JAMA. 1974;229(7):825-826. doi:10.1001/jama.1974.03230450057032
Abstract

Common 

  1. Lymphoma

  2. Metastatic melanoma

  3. Spindle cell tumor, benign or malignant

Uncommon 

  1. Aberrant pancreas

  2. Carcinoid tumor

  3. Carcinoma

  4. Eosinophilic granuloma

  5. Kaposi sarcoma

  6. Metastases from kidney, breast, or other tumors

Diagnosis.—  Metastatic melanoma.

Comment.—  Three years earlier, the patient had had a mole removed from the right preauricular area that proved to be a malignant melanoma. Over the next three years she developed metastatic melanoma to multiple sites, including the small bowel.1The "bull's-eye" lesion of the gastrointestinal tract has been so named because it appears as a large, centrally located accumulation of barium within an ulceration or a depression in the surface of a nodule. The finding of many "bull's-eye" lesions of varying sizes most likely results from metastatic melanoma; when there is a history of excision of melanoma, the diagnosis is virtually certain.Numerous "bull's-eye" lesions of the same size and limited to one or several segments of the bowel

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