To the Editor.—
The report of comparative tuberculin reactions by Erdtmann, Dixon, and Llewellyn (228:479, 1974) is a welcome study in individuals without proven pulmonary tuberculosis. We have done a similar study in a population without pulmonary tuberculosis, not suspect, and not known contacts of tuberculosis patients. Our interest arose when it became evident that some of our lepromatous leprosy patients could not be tested with tuberculin stabilized by polysorbate 80 (Tween 80), the antigen recently recommended for routine use.Of other studies comparing tuberculins in patients with proven tuberculosis,1,2 none has dealt with the comparison of reactions elicited by different tuberculins in patients without active tuberculosis or suspicion thereof. Could the reactions elicited by the Parke-Davis & Co., 5-tuberculin unit (tu) PPD pill be established as valid in those patients lost to further observation?Twenty-three patients with lepromatous leprosy and 49 with diverse illnesses were tested. Tuberculin, purified
Rea TH, Seltzer R, Levan NE. Comparative Tuberculin Reactions. JAMA. 1974;229(9):1165. doi:10.1001/jama.1974.03230470017003
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