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November 7, 1977

Medical News

JAMA. 1977;238(19):1997-2006. doi:10.1001/jama.1977.03280200009001

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Uremia conference marks progress in understanding, therapy of disease  The timing, frequency, and number of transfusions before and after kidney transplantation is the key to high rates of graft survival, according to a French investigator who has conducted a long-term study.Dr Herve Betuel, from the Blood Transfusion Center in Lyon, said that patients receiving ten transfusions before and after transplantation (more than usually given) achieved a 66% graftsurvival rate, compared with from 46% to 56% for those receiving fewer transfusions. Patients who did not receive transfusions, on the other hand, had only a 38% graft-survival rate. Dr Betuel gave his report at an international conference on uremia in Capri, Italy.The timing of transfusions before the transplantation procedure, Dr Betuel added, is of critical importance in achieving a high graft-survival rate."In our experience," he reported, "there is an overall tendency for improved graft survival in those transfused