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Article
September 2, 1974

Vinyl Chloride and Liver Tumors

Author Affiliations

Hospital of the Good Samaritan Medical Center Los Angeles

JAMA. 1974;229(10):1286. doi:10.1001/jama.1974.03230480014014

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Abstract

To the Editor.—  The article, "Angiosarcoma of the Liver Following Vinyl Chloride Exposure," by Dr. J. B. Block (229:53, 1974) is of considerable importance in view of the recently recognized relation between exposure to vinyl chloride and angiosarcoma of the liver.It is unfortunate, however, that in the "Comment" a number of incorrect statements and classifications are used.Primary carcinoma of the liver (sometimes called Kupffer cell sarcoma, hemangioendothelioma, angiosarcoma, angiomatous mesenchymoma, or hemangioblastoma) is uncommon in this country, and primary carcinoma of mesodermal origin is extremely rare. To date, 43 of these tumors in adults have been reported in the world literature.

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