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September 2, 1974

Salmonellosis and Shigellosis at Boston City Hospital: Part 2. Susceptibility of Strains of Salmonellae and Shigellae to Antibacterial Agents

Author Affiliations

From the Channing Laboratory, Thorndike Memorial Laboratory, Harvard Medical Unit, Boston City Hospital, and the Department of Medicine, Harvard Medical School, Boston. Dr. Finland is a Distinguished Physician with the US Veterans Administration.

JAMA. 1974;229(10):1309-1312. doi:10.1001/jama.1974.03230480025023

Tests for susceptibility to 57 antibacterial agents were carried out with recent isolates of salmonellae and shigellae from patients at Boston City Hospital. Except for small proportions of the strains of Salmonella resistant to penicillin, streptomycin, and tetracyclines, and larger proportions of those of Shigella resistant to streptomycin and tetracycline, the strains were uniformly susceptible, though in varying degrees, to each of the agents tested except sulfamethoxazole. These results do not support the basis for the recommendation to the Food and Drug Administration (FDA) to discontinue the use of certain antibacterial agents as feed supplements for growth promotion and increased feed efficiency in animals.

(JAMA 229:1309-1312, 1974)