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November 14, 1977

Triamcinolone AerosolTreatment of Aspirin-Hypersensitive Asthmatic Patients

JAMA. 1977;238(20):2174-2175. doi:10.1001/jama.1977.03280210066027

The efficacy of triamcinolone acetonide aerosol in the management of asthma in six patients with aspirin hypersensitivity was evaluated during a one-year trial. Five patients were previously chronically dependent on systemic corticosteroids and had undergone unsuccessful trials with cromolyn sodium therapy. Substantial reduction in corticosteroid requirements was observed; in two patients, oral prednisone therapy was completely eliminated. Forced expiratory volume and flow were maintained at levels better than those recorded before triamcinolone therapy throughout the year of follow-up. No substantial side effects due to triamcinolone were observed.

(JAMA 238:2174-2175, 1977)