BONE involvement in Hodgkin's disease does not usually occur in its early stage.1 The "ivory" appearance of the vertebra is the result of a purely sclerotic change in the bone. This occurs in 10% to 15% of cases. Local pain, when present, may disappear following radiation therapy. However, the response of the ivory vertebra to therapy has not received wide comment. We report the case of a patient with Hodgkin's disease who had an ivory vertebra. Following radiation therapy, the bone was completely restored to its normal architecture.
Report of a Case
A 23-year-old man had had back pain of several months' duration. Examination showed enlarged supraclavicular lymph glands.A biopsy specimen from a lymph gland showed nodular sclerotic Hodgkin's disease. A chest roentgenogram was normal. In May 1974, lymphangiography was performed. No pathologic findings were noted at that time. However, the 11th dorsal vertebra was found to be
Hertz M, Solomon A, Aghal E. 'Ivory Vertebra' in Hodgkin's DiseaseRestoration of Trabecular Pattern After Therapy. JAMA. 1977;238(22):2402. doi:10.1001/jama.1977.03280230066028
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