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November 28, 1977

'Ivory Vertebra' in Hodgkin's DiseaseRestoration of Trabecular Pattern After Therapy

JAMA. 1977;238(22):2402. doi:10.1001/jama.1977.03280230066028

BONE involvement in Hodgkin's disease does not usually occur in its early stage.1 The "ivory" appearance of the vertebra is the result of a purely sclerotic change in the bone. This occurs in 10% to 15% of cases. Local pain, when present, may disappear following radiation therapy. However, the response of the ivory vertebra to therapy has not received wide comment. We report the case of a patient with Hodgkin's disease who had an ivory vertebra. Following radiation therapy, the bone was completely restored to its normal architecture.

Report of a Case  A 23-year-old man had had back pain of several months' duration. Examination showed enlarged supraclavicular lymph glands.A biopsy specimen from a lymph gland showed nodular sclerotic Hodgkin's disease. A chest roentgenogram was normal. In May 1974, lymphangiography was performed. No pathologic findings were noted at that time. However, the 11th dorsal vertebra was found to be