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December 5, 1977

Bowel Perforation With Candidiasis

JAMA. 1977;238(23):2520-2521. doi:10.1001/jama.1977.03280240066024

Spontaneous multiple jejunal perforations developed in a relatively normal patient. Candida albicans was cultured from a biopsy specimen of an area of perforation and from peritoneal fluid. Yeasts and pseudohyphae were seen deep within the necrotic mucosa. Serial determinations of precipitating and agglutinating antibodies support the diagnosis of invasive candidiasis causing this unusual presentation.

(JAMA 238:2520-2521, 1977)