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October 7, 1974

Medical News

JAMA. 1974;230(1):11-28. doi:10.1001/jama.1974.03240010005001

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Scientists assess present status of cellular membrane studies  Things are happening rapidly in cell-surface research.That is why an international group of about 50 biological scientists met recently at the National Institutes of Health.Increasing evidence suggests that changes in cell membranes—especially on the cell surface— are a key to the regulation and growth of cells in animals and man. The next logical question then concerns the role of the cell surface in a cell's transformation from normal to malignant. Investigators are not sure of the answer, but they have some tantalizing hints.This was a good time to hold such a meeting, the scientists agreed. Developments in several areas of this complex, sometimes-frustrating field needed a general tying-together.The past five years have seen a virtual explosion in the technology needed to get at information about cell surfaces. Until the late 1960s it was simply not possible to