The effect of miconazole nitrate applied topically to problem dermatophyte infections (primarily tinea cruris) was studied in double-blind clinical trials. A 2% cream preparation was compared against its vehicle in 62 men. The miconazole treatment was both clinically and mycologically effective in more than 90% of the active treatment group (vs less than 20% in the placebo control group) with prompt relief of symptoms. More important, there was but a single recurrence of disease in the miconazole group during the month after therapy was stopped.
(JAMA 230:72-75, 1974)
Mandy SJ, Garrott TC. Miconazole Treatment for Severe Dermatophytoses. JAMA. 1974;230(1):72–75. doi:10.1001/jama.1974.03240010040026
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: