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October 7, 1974

Antibody Response to Cannabis

Author Affiliations

From the Division of Clinical Hematology, Department of Medicine, Michael Reese Medical Center (Drs. Shapiro and Billings), and the Michael Reese Blood Center (Drs. Orlina and Ms Unger), Chicago.

JAMA. 1974;230(1):81-82. doi:10.1001/jama.1974.03240010049030

Cannabis metabolites are antigenic and capable of eliciting an immune response. With the indirect Coombs test, humoral antibodies were found in 15 of 17 subjects who were habitual smokers of the plant. The relationship of cannabis-induced antibody formation to clinical disease was not determined.

(JAMA 230:81-82, 1974)