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October 14, 1974

Single Coronary Artery: Analysis of the Anatomic Variation, Clinical Importance, and Report of Five Cases

Author Affiliations

From the Department of Pathology, Good Samaritan Hospital, Los Angeles (MAJ Sharbaugh), and the Cardiology Service, Department of Medicine, Letterman Army Medical Center, San Francisco (Dr. White). MAJ Sharbaugh is now with the Department of Pathology, US Army Medical Center, Fort Gordon, Ga. Dr. White is now with the McKay-Dee Hospital, Ogden, Utah.

JAMA. 1974;230(2):243-246. doi:10.1001/jama.1974.03240020033019

Two of five cases of single coronary artery had additional cardiac anomalies. A review of the literature yielded 159 cases, 41% of which had additional cardiac anomalies. The presence of a single coronary artery without other cardiac defects (59%) was usually an innocuous finding. However, a small group of 13 cases without other anomalies were associated with sudden death or cardiomyopathy in young adulthood or childhood. Hence, we think that the presence of this anomaly is of prognostic importance, and that interest in it should be maintained.

(JAMA 230:243-246, 1974)