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October 21, 1974

Prevention of Arteriovenous Shunt Clotting

Author Affiliations

From the Nephrology Unit (Dr. Modai), the Department of Hematology (Dr. Leiba), and the Department of Medicine A (Dr. Alkan), Asaf Harofe Government Hospital and Tel Aviv University Medical School (Drs. Leiba and Alkan), Zerifin, Israel.

JAMA. 1974;230(3):427-430. doi:10.1001/jama.1974.03240030045025

Two patients on maintenance hemodialysis developed recurrent clotting of an arteriovenous shunt. Anticoagulant therapy was complicated by massive gastrointestinal bleeding. Very small doses of heparin sodium administered into both shunt limbs maintained patency while bleeding ceased.

(JAMA 230:427-430, 1974)