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Article
October 21, 1974

Dark Plaques in Nether Regions: A Sign of Carcinoma in Situ

JAMA. 1974;230(3):439-440. doi:10.1001/jama.1974.03240030057030
Abstract

UNDER the title "Multicentric Pigmented Bowen's Disease of the Groin," Lloyd1 reported a case of squamous cell carcinoma in situ in a 22-year-old Yemenite man. The eruption consisted of jet-black plaques on either side of the scrotum and inner aspects of the thighs. The plaques were sharply demarcated, with the larger lesions coalescing and showing a velvety surface. Matta and Kaidbey2 described a 32-year-old Lebanese man who had two brownish-black pruritic plaques of the prepuce. Both patients had biopsy specimens that showed Bowen disease, with an increased amount of epidermal and dermal pigment.

I report two cases of similar multicentric eruptions in female patients.

Report of Cases 

Case 1.—  A 37-year-old white woman had a leukoplakic area of the vulva. Bowen disease was diagnosed on biopsy. A radical vulvectomy and an inguinal and iliac lymphadenectomy were performed. The pathologic report was carcinoma in situ without invasion and without

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