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January 9, 1978

Medical Immunology

Author Affiliations

Wayne State University School of Medicine Detroit

JAMA. 1978;239(2):145. doi:10.1001/jama.1978.03280290065030

The rapid growth of immunology during the past years has led to a profusion of new textbooks, most of which have tried to cover the entire scope of immunology. The three authors of Medical Immunology, however, have perceived a gap owing to the absence of an early readable book devoted to the clinical applications of immunology. They have been able to fill the void with a useful book of manageable size.

Immunology begins with the study of acquired resistance to infectious diseases, a subject that still occupies an important place in clinical immunology. These studies led to the realization that the immune response is a complex apparatus with built-in checks and balances. The physiological regulators sometimes go awry and cause disease or contribute to it. Most of the book is concerned with defects in immunologic regulation in the form of immunodeficiency diseases, immunoproliferative diseases, immune complex diseases, and autoimmune diseases.