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October 28, 1974

Penicillin-Resistant Staphylococci

JAMA. 1974;230(4):539. doi:10.1001/jama.1974.03240040017014

To the Editor.—  In the recent article by Ross et al (229:1075, 1974), 84% of the staphylococcal (Staphylococcus aureus) isolates from community-acquired infections in children were found to be resistant to penicillin. This is similar to our findings in an adult population. Data obtained from our surveillance program from February 1973 to May 1974 (16 months) showed that 82 patients were admitted to the hospital with community-acquired S aureus infections. In 51 patients (62%), the S aureus isolated was resistant to penicillin. All patients who were recently discharged from the hospital or who had ongoing chronic infection were excluded from this study. Sensitivity testing was performed by serial agar diffusion in Mueller-Hinton agar, using a Sears replicator. Those organisms whose growth was not inhibited by 1.0μg/ml of penicillin were considered resistant. A few staphylococcal isolates were tested by the Kirby-Bauer Method, using the standard 10-unit disk of penicillin. A