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October 28, 1974

Serum Creatinine, Urea, and Protein Level Changes in Hydatidiform Mole

Author Affiliations

From the Department of Human Ecology, School of Public Health, Nutrition Section (Dr. Vaghefi and Ms. Agheli), and the Department of Gynecology and Obstetrics (Dr. Pour-Reza), University of Tehran, Tehran, Iran.

JAMA. 1974;230(4):580-581. doi:10.1001/jama.1974.03240040050033

In a study of nonprotein nitrogen, total protein albumin, and globulin levels in 25 patients with hydatidiform mole, serum creatinine and urea concentrations were found to be significantly increased and total protein and albumin levels decreased. These levels, compared with those found among 150 healthy women in the first trimester of pregnancy, appear to confirm reports that protein deficiencies favor occurrence of hydatidiform mole.

(JAMA 230:580-581, 1974)