This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
Eighteen years have past since the section on the CNS in the Handbook of Physiology was published. The first two volumes dealing with the CNS have now appeared under the title of Cellular Biology of Neurons. This choice in itself reflects the growth of knowledge of neurophysiology as well as its extension into new realms that could certainly not have been predicted. The roster of contributors guarantees the quality of contents.
These volumes clearly bear witness to the truly amazing discoveries that have been made possible by the introduction of a large number of new investigative techniques such as electron microscopy, freeze-fracture methods, tissue culture, tetrodotoxin-binding, and intracellular recording. While the previous emphasis on the biophysics of excitable membranes has not been lost, advances in the study of ultrastructure, biochemistry, and the pharmacology of neurotransmitters have considerably broadened the scope of what will undoubtedly become as much of a classic
Poser CM. Handbook of Physiology: A Critical, Comprehensive Presentation of Physiological Knowledge and Concepts, section 1: The Nervous System, vol 1: Cellular Biology of Neurons. JAMA. 1978;239(6):548–549. doi:10.1001/jama.1978.03280330080045
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: