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November 18, 1974


Author Affiliations

Chairman Medical Research Awards Jury New York City, November 14, 1974

JAMA. 1974;230(7):1023-1024. doi:10.1001/jama.1974.03240070055037

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John Charnley, DSc, FRCS  Professor Charnley receives the Albert Lasker Clinical Medical Research Award for his original, innovative concepts for total prosthetic joint replacement, developed during the 1950s, which have had a major impact on improving the treatment and rehabilitation of patients with crippling joint diseases—especially arthritis.Combining his talents as an orthopedic surgeon and biomedical engineer, Professor Charnley conducted original laboratory and clinical research in joint lubrication and the biomedical characteristics of joint opposition. The investigations led to the development of a revolutionary design of a total hip joint replacement and the introduction of the use of methyl methacrylate as a plastic cement to firmly affix the prosthetic components to the bone.Although the pioneering work on joint prosthetics going back to 1908 cannot be ignored, the present advances were made possible by Professor Charnley's unique concepts. The techniques and concepts that he introduced in 1961 have given patients