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November 25, 1974

Evaluation of a New Topical Agent for Burn Therapy: Silver Sulfadiazine (Silvadene)

Author Affiliations

Dr. Ballin is Director, AMA Department of Drugs. This communication was prepared with the assistance of consultants.

JAMA. 1974;230(8):1184-1185. doi:10.1001/jama.1974.03240080064038

Silver sulfadiazine is a new topical antimicrobial agent that is used effectively to prevent and treat sepsis in patients with second- and third-degree burns. Because of its low toxicity, relative freedom from complications, and wide spectrum of antimicrobial activity, silver sulfadiazine represents an advance in the pharmacologic management of the burned patient.

(JAMA 230:1184-1185, 1974)