Five tables suggest maintenance dosage intervals for common drugs used in patients with renal insufficiency, based on data in the literature. If information about a particular drug is unavailable, emphasis is given to biological half-life, normal pharmacology, and creatinine clearance for modification of the usual dose schedules. Nephrotoxicity or adverse effects in patients with renal disease are noted and adjustments for concurrent dialysis suggested.
(JAMA 230:1544-1553, 1974)
Bennett WM, Singer I, Coggins CJ. A Guide to Drug Therapy in Renal Failure. JAMA. 1974;230(11):1544–1553. doi:10.1001/jama.1974.03240110036016
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