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December 16, 1974

Digoxin Absorption From Tablets and Elixir: The Effect of Radiation-Induced Malabsorption

Author Affiliations

From the Clinical Pharmacokinetics Laboratory, departments of medicine (Drs. Conti, Molson, Kuritzky, Giller, and Schultz), and pharmaceutics (Dr. Jusko), Millard Fillmore Hospital and State University of New York at Buffalo, Buffalo, NY.

JAMA. 1974;230(11):1554-1555. doi:10.1001/jama.1974.03240110046017

A patient with a radiation-induced malabsorption syndrome absorbed digoxin poorly from a tablet preparation. Substitution of digoxin elixir overcame the bioavailability problem.

(JAMA 230:1554-1555, 1974)