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December 16, 1974

Hepatic Function in Acute Myocardial Infarction

Author Affiliations

From the Division of Cardiology, Veterans Administration Hospital, Allen Park, Mich, and the Wayne State University School of Medicine, Detroit (Dr. Das), and the St. Barnabas Medical Center, Livingston, NJ (Drs. Nussbaum and Leff).

JAMA. 1974;230(11):1558-1560. doi:10.1001/jama.1974.03240110050019

Hepatic function was evaluated in 17 patients with acute myocardial infarction by measuring sulfobromophthalein retention, serum glutamic pyruvic transaminase level, lactic dehydrogenase (LDH ) hepatic isoenzyme, serum bilirubin value, and urinary urobilinogen excretion. Statistically significant alterations in the hepatic function were observed during the acute stage of the infarct as compared to the period following recovery. Hemodynamic changes in patients with acute myocardial infarction may play an important role in the genesis of altered hepatic function.

(JAMA 230:1558-1560, 1974)